Altered Cisatracurium Pharmacokinetics and Pharmacodynamics in Patients with Congenital Heart Defects

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Altered Cisatracurium Pharmacokinetics and Pharmacodynamics in Patients with Congenital Heart Defects.

The neuromuscular blocking agent cisatracurium is frequently used adjunctively in anesthesia to facilitate endotracheal intubation and to provide muscle relaxation during surgery. We aimed to determine the pharmacokinetics (PK)/pharmacodynamics (PD) of cisatracurium in patients with congenital heart defects (CHDs), such as ventricular septal defects and atrial septal defects, and to assess the ...

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The Prevalence of Celiac Disease in Down syndrome Children with and without Congenital Heart Defects

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ژورنال

عنوان ژورنال: Drug Metabolism and Disposition

سال: 2015

ISSN: 1521-009X

DOI: 10.1124/dmd.115.067405